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Silence Therapeutics plc is projected to rise to $12.32 by 2027, a +17% move from its current price of $10.49. SLN is currently trading above its 50-day average (a bullish sign). Technical indicators currently lean buy.
A data-driven summary — not financial advice. See the full breakdown below.
Live market data via Yahoo Finance · updated 8/1/2026
| Period | Min | Prediction | Max | Change |
|---|---|---|---|---|
| Aug 3 | $10.01 | $10.49 | $10.99 | -0.01% |
| Aug 4 | $9.82 | $10.49 | $11.20 | -0.01% |
| Aug 5 | $9.68 | $10.49 | $11.37 | -0.02% |
| Aug 6 | $9.56 | $10.49 | $11.51 | -0.02% |
| Aug 7 | $9.45 | $10.49 | $11.64 | -0.03% |
| Aug 8 | $9.36 | $10.49 | $11.75 | -0.03% |
| Aug 9 | $9.27 | $10.49 | $11.86 | -0.04% |
| Period | Min | Prediction | Max | Change |
|---|---|---|---|---|
| Week 1 | $9.27 | $10.49 | $11.86 | -0.04% |
| Week 2 | $8.81 | $10.48 | $12.47 | -0.08% |
| Week 3 | $8.47 | $10.48 | $12.96 | -0.12% |
| Week 4 | $8.19 | $10.47 | $13.39 | -0.15% |
| Week 5 | $7.95 | $10.47 | $13.78 | -0.19% |
| Week 6 | $7.74 | $10.47 | $14.14 | -0.23% |
| Week 7 | $7.56 | $10.46 | $14.48 | -0.27% |
Short-term targets derived from the forecast trend and recent volatility. Highly uncertain — not financial advice.
Silence Therapeutics plc is a biotechnology company that engages in the discovery and development of novel molecules incorporating short interfering ribonucleic acid (siRNA) to inhibit the expression of specific target genes in hematology, cardiovascular, and rare diseases.
The company develops Divesiran (SLN124), which is in Phase 2 development for polycythemia vera, and SLN548 for complement-mediated renal diseases. It also develops Zerlasiran (SLN360) for cardiovascular disease associated with elevated lipoprotein(a); SLN312 for dyslipidemia; SLN365 for hypercholesterolemia; and SLN098 for obesity.
The company was formerly known as SR Pharma plc and changed its name to Silence Therapeutics plc in May 2007. Silence Therapeutics plc was incorporated in 1994 and is headquartered in London, United Kingdom.
Silence Therapeutics plc (SLN) is currently priced at $10.49 and has a market capitalization of $495.49M.
It is ranked 2914 by market cap.
The forecasted price path shows the current price wrapping into a longer-term rise, with 2026 averaging $10.49 and 2027 averaging $12.32, 2028 averaging $17.57, and 2030 averaging $27.05, extending to 2050 averaging $166.84.
This points to a long-term bullish stance, though near-term momentum in 2026 is neutral before turning bullish in subsequent years.
A major floor 55.3% below — a decisive break under it would weaken the trend.
The nearest floor, 33.9% below — buyers have tended to step in here.
The nearest ceiling, 15.1% above — a clean break opens room to run.
A major ceiling 42.7% above — clearing it would confirm fresh momentum.
Key SLN support and resistance from recent price action — levels where the trend has historically paused or reversed. Percentages are the distance from the current price.
A snapshot of SLN market posture derived from its technical indicators and recent volatility. Higher trend and alignment lean bullish; higher risk means larger swings.
Technical Analysis
Indicators computed on daily closing prices.
| Period | SMA | Action | EMA | Action |
|---|---|---|---|---|
| MA 5 | $11.46 | Sell | $11.19 | Sell |
| MA 10 | $11.29 | Sell | $11.13 | Sell |
| MA 20 | $10.67 | Sell | $10.66 | Sell |
| MA 50 | $8.75 | Buy | $9.34 | Buy |
| MA 100 | $7.68 | Buy | $8.19 | Buy |
| MA 200 | $6.85 | Buy | $7.38 | Buy |
| Name | Value | Action |
|---|---|---|
| RSI (14) | 51.66 | Neutral |
| Stoch RSI (14) | 0.00 | Buy |
| CCI (20) | -17.93 | Neutral |
| Williams %R (14) | -68.10 | Info |
| MACD (12,26,9) | -0.09 | Sell |
| ROC (12) | 0.38 | Buy |
| Bollinger %B (20,2) | 0.44 | Neutral |
| Stochastic %K (14) | 31.90 | Neutral |
| TRIX (15) | 1.29 | Buy |
| Awesome (5,34) | 1.62 | Buy |
| Ultimate (7,14,28) | 43.34 | Neutral |
| Momentum (10) | -0.01 | Sell |
| Aroon Osc (25) | 44.00 | Buy |
| Hull MA (9) | 11.34 | Sell |
| ADX (14) | 25.93 | Buy |
| ATR (14) | 0.46 | Info |
The 30-day technical picture is bullish with a neutral momentum nuance.
RSI14 is 50, and the price sits above both the SMA50 ($8.75) and the SMA200 ($6.85).
Key near-term levels: support at $6.93 and resistance at $12.07, with a 30-day price range of $7.72 to $14.25. The stock’s annualized volatility is 90%.
| Year | Min | Avg | Max | ROI | Sentiment |
|---|---|---|---|---|---|
| $4.30 | $10.49 | $12.77 | 0% | Neutral | |
| $9.20 | $12.32 | $17.76 | +17% | Neutral | |
| $12.45 | $17.57 | $26.85 | +67% | Bullish | |
| $14.90 | $21.97 | $35.10 | +109% | Bullish | |
| $17.64 | $27.05 | $44.83 | +158% | Bullish | |
| $17.56 | $27.92 | $47.77 | +166% | Bullish | |
| $17.70 | $29.13 | $51.26 | +178% | Bullish | |
| $19.57 | $33.30 | $60.11 | +217% | Bullish | |
| $19.08 | $33.50 | $61.88 | +219% | Bullish | |
| $23.88 | $43.25 | $81.61 | +312% | Bullish | |
| $31.54 | $66.17 | $136.26 | +531% | Bullish | |
| $75.08 | $166.84 | $383.72 | +14.9x | Bullish |
Current year — the forecast is anchored to the live price, so ROI shows 0%.
| Month | Min | Avg | Max | Change |
|---|---|---|---|---|
| August 2026 | $4.30 | $10.49 | $12.54 | +0.00% |
| September 2026 | $8.26 | $9.98 | $12.54 | -4.84% |
| October 2026 | $8.54 | $10.44 | $13.35 | +4.56% |
| November 2026 | $8.43 | $10.40 | $13.49 | -0.34% |
| December 2026 | $7.81 | $9.73 | $12.77 | -6.49% |
Click any year to see its month-by-month SLN forecast. Min / Avg / Max are a bear / base / bull scenario; ROI is the projected move from the current price. Change is the month-over-month move in the average. Estimates, not guarantees.
By 2026, SLN could reach as high as $12.77, with a base case around $10.49 and support toward $4.30 — roughly 0% from $10.49. Price action looks broadly range-bound.
Expect SLN to range from $9.20 to $17.76 through 2027. The $12.32 average target implies a +17% move from current prices. That is up +17% on the projected 2026 average. A consolidation phase looks the most probable path here.
The SLN price prediction for 2028 points to an average of $17.57 (low $12.45, high $26.85) — a potential gain of +67% on today's $10.49. Momentum favours further upside here.
In 2029, SLN is projected to trade between $14.90 and $35.10, averaging $21.97 — a potential gain of +109% from today's $10.49. That is up +25% on the projected 2028 average. Buyers look set to stay in control over this stretch.
Silence Therapeutics plc's 2030 outlook centres on $27.05, within a $17.64 to $44.83 range. That is up +23% on the projected 2029 average. That marks a +158% change versus current levels. Momentum favours further upside here.
By 2031, SLN could reach as high as $47.77, with a base case around $27.92 and support toward $17.56 — roughly +166% from $10.49. Buyers look set to stay in control over this stretch.
Expect SLN to range from $17.70 to $51.26 through 2032. The $29.13 average target implies a +178% move from current prices. That is up +4% on the projected 2031 average. Momentum favours further upside here.
The SLN price prediction for 2033 points to an average of $33.30 (low $19.57, high $60.11) — a potential gain of +217% on today's $10.49. Buyers look set to stay in control over this stretch.
In 2034, SLN is projected to trade between $19.08 and $61.88, averaging $33.50 — a potential gain of +219% from today's $10.49. That is up +1% on the projected 2033 average. Momentum favours further upside here.
Silence Therapeutics plc's 2035 outlook centres on $43.25, within a $23.88 to $81.61 range. That is up +29% on the projected 2034 average. That marks a +312% change versus current levels. Buyers look set to stay in control over this stretch.
By 2040, SLN could reach as high as $136.26, with a base case around $66.17 and support toward $31.54 — roughly +531% from $10.49. Momentum favours further upside here.
Expect SLN to range from $75.08 to $383.72 through 2050. The $166.84 average target implies a +14.9x move from current prices. That is up +152% on the projected 2040 average. Buyers look set to stay in control over this stretch.
Investing $1,000 in SLN today (≈ 95.328885 SLN) could be worth
$15,904.29
+$14,904.29 (+1490%) by 2050 · US Dollar
Based on the average projected SLN price of $166.84 in 2050.
Based on the base (average) forecast scenario. FX rates are indicative. Estimates only — not financial advice.
See what a past investment in SLNwould be worth at today's price.
$1,000 invested in SLN on Jul 31, 2025 (≈ 162.337666 SLN) would be worth
$1,702.92
+$702.92 (+70.3%) today · 1.70× · US Dollar
Based on a SLN entry price of $6.16 vs. today's $10.49.
| Invested | Entry price | Value today | Return |
|---|---|---|---|
| 1 week ago | $11.02 | $951.91 | -4.8% |
| 1 month ago | $10.5 | $999.05 | -0.1% |
| 3 months ago | $7.13 | $1,471.25 | +47.1% |
| 6 months ago | $4.9 | $2,140.82 | +114.1% |
| 1 year ago | $6.16 | $1,702.92 | +70.3% |
| All time (5.0y) ago | $25.6 | $409.77 | -59.0% |
Past performance from historical market data — it does not predict future results. FX rates are indicative. Not financial advice.
Enter a price to see how it sits against our SLN forecast.
Our base-case forecast reaches $21.00 around 2029.
Implied market cap at $21.00: $991.93M
The multi-year forecast shows a rising price trajectory from 2026 onward, with the 2026 avg price at $10.49 and the 2030 avg at $27.05.
From 2031 to 2035, the averages are $27.92, $29.13, $33.30, and $33.50 respectively, with ROIs of 166.2%, 177.7%, 217.4%, and 219.4%. By 2035, the avg is $43.25 with ROI 312.3%. The 2040 projection rises to an avg of $66.17 (ROI 530.8%). By 2050, the avg reaches $166.84 with ROI 1490.4%.
Overall, the sentiment remains bullish across the longer horizon, with substantial upside implied by the tail-year forecasts, while recognizing that these figures are estimates rather than guarantees.
Tap a question to reveal the answer.
The 2030 avg price is $27.05, with a min of $17.64 and a max of $44.83. The ROI is 157.8%. The sentiment is bullish.
Forecasts show rising average prices from 2027 onward, with ROIs reaching 312.3% by 2035 and 1490.4% by 2050. Note that 2026 is neutral and 2027 is neutral before bullish momentum emerges in 2028.
Yes—the max forecast by 2040 is $136.26 and by 2050 is $383.72, so a $100 level is forecast by 2040.
Current price is $10.49 and market capitalization is $495.49M. The rank is 2914.
Avg $43.25; min $23.88; max $81.61; ROI 312.3%; sentiment bullish.
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