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Xilio Therapeutics, Inc. is projected to rise to $10.90 by 2027, a +20% move from its current price of $9.05. XLO is currently trading above its 50-day average (a bullish sign). Technical indicators currently lean strong buy.
A data-driven summary — not financial advice. See the full breakdown below.
Live market data via Yahoo Finance · updated 8/4/2026
| Period | Min | Prediction | Max | Change |
|---|---|---|---|---|
| Aug 5 | $8.88 | $9.06 | $9.24 | +0.11% |
| Aug 6 | $8.81 | $9.07 | $9.33 | +0.22% |
| Aug 7 | $8.77 | $9.08 | $9.40 | +0.32% |
| Aug 8 | $8.73 | $9.09 | $9.46 | +0.43% |
| Aug 9 | $8.70 | $9.10 | $9.52 | +0.54% |
| Aug 10 | $8.67 | $9.11 | $9.57 | +0.65% |
| Aug 11 | $8.64 | $9.12 | $9.62 | +0.76% |
| Period | Min | Prediction | Max | Change |
|---|---|---|---|---|
| Week 1 | $8.64 | $9.12 | $9.62 | +0.76% |
| Week 2 | $8.52 | $9.19 | $9.91 | +1.52% |
| Week 3 | $8.44 | $9.26 | $10.15 | +2.28% |
| Week 4 | $8.38 | $9.33 | $10.38 | +3.06% |
| Week 5 | $8.34 | $9.40 | $10.59 | +3.83% |
| Week 6 | $8.31 | $9.47 | $10.79 | +4.62% |
| Week 7 | $8.28 | $9.54 | $10.99 | +5.41% |
Short-term targets derived from the forecast trend and recent volatility. Highly uncertain — not financial advice.
Xilio Therapeutics, Inc. is a clinical-stage biotechnology company focused on discovering and developing masked immuno-oncology therapies. Its pipeline includes XTX501, a bispecific PD-1 / masked IL-2, for patients with metastatic non-small cell lung cancer; Efarindodekin alfa, an investigational, masked IL-12, that is in Phase 2 clinical trial for patients with advanced solid tumors; and Vilastobart, an investigational tumor-activated, Fc-enhanced, high affinity binding anti-CTLA-4 monoclonal antibody.
The company was founded in 2016 and is headquartered in Waltham, Massachusetts.
Xilio Therapeutics, Inc. trades under the symbol XLO and is currently priced at $9.09. Its market capitalization is $59.77M, and it ranks 4285 by market cap. The current price is complemented by a neutral near-term technical posture and a defined 30-day trading range.
Forecasts show a multi-year upside path, with the average price moving higher across the horizon. The 2026 average is $9.09 and the trajectory extends to $62.48 at the 2050 horizon, with yearly max prices signaling meaningful upside along with rising ROIs.
A major floor 15.1% below — a decisive break under it would weaken the trend.
The nearest floor, 8.2% below — buyers have tended to step in here.
The nearest ceiling, 5.9% above — a clean break opens room to run.
A major ceiling 13.5% above — clearing it would confirm fresh momentum.
Key XLO support and resistance from recent price action — levels where the trend has historically paused or reversed. Percentages are the distance from the current price.
A snapshot of XLO market posture derived from its technical indicators and recent volatility. Higher trend and alignment lean bullish; higher risk means larger swings.
Technical Analysis
Indicators computed on daily closing prices.
| Period | SMA | Action | EMA | Action |
|---|---|---|---|---|
| MA 5 | $9.11 | Sell | $9.04 | Buy |
| MA 10 | $8.82 | Buy | $8.97 | Buy |
| MA 20 | $8.99 | Buy | $8.93 | Buy |
| MA 50 | $8.71 | Buy | $8.76 | Buy |
| MA 100 | $8.42 | Buy | $8.67 | Buy |
| MA 200 | $8.93 | Buy | $9.02 | Buy |
| Name | Value | Action |
|---|---|---|
| RSI (14) | 55.31 | Neutral |
| Stoch RSI (14) | 94.49 | Sell |
| CCI (20) | 32.76 | Neutral |
| Williams %R (14) | -4.76 | Info |
| MACD (12,26,9) | 0.01 | Buy |
| ROC (12) | -0.11 | Sell |
| Bollinger %B (20,2) | 0.60 | Neutral |
| Stochastic %K (14) | 95.24 | Sell |
| TRIX (15) | 0.09 | Buy |
| Awesome (5,34) | 0.16 | Buy |
| Ultimate (7,14,28) | 65.68 | Neutral |
| Momentum (10) | 0.23 | Buy |
| Aroon Osc (25) | -64.00 | Sell |
| Hull MA (9) | 9.26 | Sell |
| ADX (14) | 13.96 | Neutral |
| ATR (14) | 0.16 | Info |
The near-term technical picture is NEUTRAL with RSI at 60. The price sits between key moving averages, with SMA50 at $8.65 and SMA200 at $8.97.
Near-term support is $8.25 and resistance is $9.58. The 30-day range runs from $7.82 to $10.56, indicating a bounded drift around the current level.
| Year | Min | Avg | Max | ROI | Sentiment |
|---|---|---|---|---|---|
| $7.14 | $9.11 | $12.64 | 0% | Neutral | |
| $8.90 | $10.90 | $13.97 | +20% | Neutral | |
| $9.44 | $11.80 | $15.57 | +29% | Bullish | |
| $10.15 | $12.91 | $17.42 | +42% | Bullish | |
| $10.24 | $13.20 | $18.17 | +45% | Bullish | |
| $10.93 | $14.28 | $19.98 | +57% | Bullish | |
| $12.62 | $16.69 | $23.70 | +83% | Bullish | |
| $14.72 | $19.70 | $28.37 | +116% | Bullish | |
| $15.59 | $21.08 | $30.74 | +131% | Bullish | |
| $15.58 | $21.29 | $31.41 | +134% | Bullish | |
| $22.41 | $32.06 | $49.71 | +252% | Bullish | |
| $38.30 | $59.15 | $98.68 | +549% | Bullish |
Current year — the forecast is anchored to the live price, so ROI shows 0%.
| Month | Min | Avg | Max | Change |
|---|---|---|---|---|
| August 2026 | $7.14 | $9.11 | $11.24 | +0.66% |
| September 2026 | $8.43 | $9.90 | $11.89 | +8.62% |
| October 2026 | $8.46 | $9.98 | $12.09 | +0.88% |
| November 2026 | $8.45 | $10.01 | $12.20 | +0.31% |
| December 2026 | $8.67 | $10.31 | $12.64 | +2.97% |
Click any year to see its month-by-month XLO forecast. Min / Avg / Max are a bear / base / bull scenario; ROI is the projected move from the current price. Change is the month-over-month move in the average. Estimates, not guarantees.
By 2026, XLO could reach as high as $12.64, with a base case around $9.11 and support toward $7.14 — roughly 0% from $9.05. Price action looks broadly range-bound.
Expect XLO to range from $8.90 to $13.97 through 2027. The $10.90 average target implies a +20% move from current prices. That is up +20% on the projected 2026 average. A consolidation phase looks the most probable path here.
The XLO price prediction for 2028 points to an average of $11.80 (low $9.44, high $15.57) — a potential gain of +29% on today's $9.05. Momentum favours further upside here.
In 2029, XLO is projected to trade between $10.15 and $17.42, averaging $12.91 — a potential gain of +42% from today's $9.05. That is up +9% on the projected 2028 average. Buyers look set to stay in control over this stretch.
Xilio Therapeutics, Inc.'s 2030 outlook centres on $13.20, within a $10.24 to $18.17 range. That is up +2% on the projected 2029 average. That marks a +45% change versus current levels. Momentum favours further upside here.
By 2031, XLO could reach as high as $19.98, with a base case around $14.28 and support toward $10.93 — roughly +57% from $9.05. Buyers look set to stay in control over this stretch.
Expect XLO to range from $12.62 to $23.70 through 2032. The $16.69 average target implies a +83% move from current prices. That is up +17% on the projected 2031 average. Momentum favours further upside here.
The XLO price prediction for 2033 points to an average of $19.70 (low $14.72, high $28.37) — a potential gain of +116% on today's $9.05. Buyers look set to stay in control over this stretch.
In 2034, XLO is projected to trade between $15.59 and $30.74, averaging $21.08 — a potential gain of +131% from today's $9.05. That is up +7% on the projected 2033 average. Momentum favours further upside here.
Xilio Therapeutics, Inc.'s 2035 outlook centres on $21.29, within a $15.58 to $31.41 range. That is up +1% on the projected 2034 average. That marks a +134% change versus current levels. Buyers look set to stay in control over this stretch.
By 2040, XLO could reach as high as $49.71, with a base case around $32.06 and support toward $22.41 — roughly +252% from $9.05. Momentum favours further upside here.
Expect XLO to range from $38.30 to $98.68 through 2050. The $59.15 average target implies a +549% move from current prices. That is up +85% on the projected 2040 average. Buyers look set to stay in control over this stretch.
Investing $1,000 in XLO today (≈ 110.497238 XLO) could be worth
$6,535.37
+$5,535.37 (+554%) by 2050 · US Dollar
Based on the average projected XLO price of $59.15 in 2050.
Based on the base (average) forecast scenario. FX rates are indicative. Estimates only — not financial advice.
See what a past investment in XLOwould be worth at today's price.
$1,000 invested in XLO on Jul 31, 2025 (≈ 110.059427 XLO) would be worth
$996.04
-$3.96 (-0.4%) today · 1.00× · US Dollar
Based on a XLO entry price of $9.09 vs. today's $9.05.
| Invested | Entry price | Value today | Return |
|---|---|---|---|
| 1 week ago | $8.65 | $1,046.24 | +4.6% |
| 1 month ago | $9.22 | $981.56 | -1.8% |
| 3 months ago | $8.32 | $1,087.74 | +8.8% |
| 6 months ago | $8.23 | $1,099.37 | +9.9% |
| 1 year ago | $9.09 | $996.04 | -0.4% |
| All time (4.8y) ago | $224 | $40.4 | -96.0% |
Past performance from historical market data — it does not predict future results. FX rates are indicative. Not financial advice.
Enter a price to see how it sits against our XLO forecast.
Our base-case forecast reaches $18.00 around 2033.
Implied market cap at $18.00: $118.35M
The multi-year forecast shows a bullish trajectory. In 2026, the average price is $9.09 with a neutral sentiment and 0% ROI. By 2027 the average is $10.91 (ROI 20%), and by 2028 it is $11.92 (ROI 31.2%).
In 2030, the average is $13.32 with a 46.5% ROI, and 2031–2035 show continued gains, culminating in 2032 with an average of $17.36 (ROI 91%) and 2035 with an average of $22.12 (ROI 143.3%). The horizon extends to 2040 with an average of $33.79 (ROI 271.7%), and 2050 projects an average of $62.48 (ROI 587.4%). The sentiment remains bullish in the later years, reflecting a strong upside potential alongside inherent uncertainty in long-run forecasts.
Tap a question to reveal the answer.
The 2030 forecast shows an average price of $13.32 with a max of $18.70 and a min of $10.17; the ROI is 46.5% and the sentiment is BULLISH.
The forecast includes rising averages and bullish sentiment from 2028 onward, with positive ROIs (e.g., 31.2% in 2028, 44.9% in 2029, 46.5% in 2030, and higher in later years). These are estimates, not guarantees, and should be weighed with risk.
Yes, the max forecast reaches $108.27 by 2050, indicating the possibility of surpassing $100 in the longer term, with a projected average of $62.48 and a 587.4% ROI.
Current price: $9.09. Market cap: $59.77M.
RSI14 is 60 and sentiment is NEUTRAL. The 30-day range is $7.82 to $10.56, with support at $8.25 and resistance at $9.58.
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